PRESS RELEASES

Shortcuts 2025 2024 2023 2022

2025

• BioCardia Reports First Quarter 2025 Business Highlights and Financial Results

• BioCardia to Host Q1 2025 Corporate Update and Financial Results Conference Call on May 14, 2025

• BioCardia Initiates Patient Enrollment at University of Wisconsin at Madison for Ongoing CardiAMP HF II Pivotal Study

• BioCardia Announces First Patient in Phase 3 Randomized Controlled Double-Blind CardiAMP HF II Clinical Trial of the Company’s Lead Cell Therapy for Treatment of Heart Failure

• BioCardia Announces Positive DSMB Review of CardiALLO Allogeneic Cell Therapy for Heart Failure Phase 1/2 Clinical Trial

• BioCardia Initiates Patient Enrollment at Emory University School of Medicine for Ongoing CardiAMP HF II Pivotal Study

• BioCardia’s Conference Call Today, Monday, March 31, 2025 to be Held at 4:30PM EDT Time Today

• BioCardia Phase 3 CardiAMP-HF Trial Of Novel Cardiac Cell Therapy For Ischemic Heart Failure Shows Increased Survival, Decreased Cardiac Events, And Improved Quality Of Life At Two Years

• BioCardia Reports 2024 Business Highlights and Financial Results

• BioCardia to Host 2024 Financial Results and Corporate Update Conference Call on March 31, 2025

• BioCardia Announces Japanese Patent for Helix™ Biotherapeutic Delivery System

• BioCardia Announces Primary Outcome Measures Data Freeze in CardiAMP Heart Failure Trial for Presentation at the American College of Cardiology 2025 Scientific Sessions

• BioCardia Reports Completion of Low Dose Cohort Enrollment for CardiALLO Phase I/II Clinical Trial of BCDA-03 Allogeneic Mesenchymal Stem Cells to Treat Ischemic Heart Failure of Reduced Ejection Fraction (HFrEF)

• BioCardia Announces Late Breaking Clinical Trial Presentation on CardiAMP Heart Failure Trial at the American College of Cardiology 2025 Scientific Sessions

2024

• BioCardia Announces Commercial Availability of Morph® DNA™ Steerable Introducer Product Family

• BioCardia Announces Positive Consultation with Japan PMDA on CardiAMP Cell Therapy for Ischemic Heart Failure

• BioCardia Reports Third Quarter 2024 Business Highlights and Financial Results

• BioCardia to Host Q3 2024 Corporate Update and Financial Results Conference Call on November 13, 2024

• BioCardia Completes Phase III Randomized Double-Blind Controlled Trial of Autologous Cell Therapy for Ischemic Heart Failure

• BioCardia Regains Full Compliance with Nasdaq Listing Requirements

• BioCardia Announces Closing of Upsized $7.2 Million Public Offering Priced At-The-Market Under Nasdaq Rules

• BioCardia Announces Pricing of Upsized $7.2 Million Public Offering Priced At-The-Market Under Nasdaq Rules

• BioCardia Announces FDA Market Clearance of Morph® DNA™ Steerable Introducer Product Family

• FDA Approves CardiAMP® Heart Failure II Protocol Amendment to Use Proprietary Cell Population Analysis Screening to Define Treatment

• BioCardia Reports Second Quarter 2024 Business Highlights and Financial Results

• BioCardia to Host Q2 2024 Corporate Update and Financial Results Conference Call on August 13, 2024

• BioCardia Submits for FDA Approval of Morph® DNA™ Steerable Introducer Product Family

• Patient Enrollment Commenced in Pivotal Phase 3 Trial of CardiAMP Cell Therapy for the Treatment of Ischemic Heart Failure

• BioCardia Announces United States Patent Issuance on Morph DNA Multi-Directional Steerable Catheter Transseptal Application

• CellProthera and BioCardia Collaborate on Successful Phase II Trial of ProtheraCytes™ for the Treatment of Acute Myocardial Infarction

• BioCardia Announces United States Patent Issuance on Intramyocardial Delivery of Cell Aggregates to the Heart Including Minimally Invasive Radial Artery Approach

• BioCardia Announces Reverse Stock Split

• BioCardia Reports First Quarter 2024 Business Highlights and Financial Results

• BioCardia to Host Q1 2024 Financial Results and Corporate Update Conference Call on May 14, 2024

• BioCardia’s CardiAMP Cell Therapy Chronic Myocardial Ischemia Trial Results Show Patient Benefits in Important Outcomes

• BioCardia Completes Enrollment of CardiAMP Cell Therapy for the Treatment of Chronic Myocardial Ischemia Trial Open Label Roll-In Cohort

• BioCardia Reports Fourth Quarter and Full Year 2023 Business Highlights and Financial Results

• BioCardia to Host 2023 Financial Results and Corporate Update Conference Call on March 27, 2024

• BioCardia and StemCardia Announce Biotherapeutic Delivery Partnership

• BioCardia Announces CMS Approval of Coverage for CardiAMP Cell Therapy Confirmatory Phase III Heart Failure Study

• BioCardia Reports Positive Interim Results from Phase III CardiAMP Cell Therapy Heart Failure Trial, with Compelling Data in Subgroup with Elevated NTproBNP Biomarker for Heart Failure

• BioCardia Announces Activation of CardiAMP Heart Failure II Phase 3 Pivotal Study Recently Approved by FDA

• BioCardia Announces Two Scientific Abstracts Have Been Accepted at the 2024 Technology and Heart Failure Therapeutics Conference

• BioCardia Biotherapeutic Delivery and Morph Access Innovations Business Development Update for Shareholders

2023

• BioCardia Doses First Patient in CardiALLO Phase I/II Clinical Trial of BCDA-03 Allogeneic Mesenchymal Stem Cells for the Treatment of Ischemic Heart Failure of Reduced Ejection Fraction

• BioCardia Announces Expected CardiAMP Heart Failure Japan Approval Timeline Based on Pharmaceutical and Medical Device Agency Consultation Minutes

• BioCardia Shares Update from Japan PMDA Consultation on CardiAMP Autologous Cell Therapy for Ischemic Heart Failure; Foreign Data Expected to be Sufficient for Product Approval

• BioCardia Announces $1.3 Million Registered Direct Offering of Common Stock Priced At-the-Market under Nasdaq Rules

• BioCardia Announces FDA Approval of CardiAMP Heart Failure II Protocol for Autologous Cell Therapy for Ischemic Heart Failure

• BioCardia Reports Third Quarter 2023 Business Highlights and Financial Results

• BioCardia to Host Q3 2023 Corporate Update and Financial Results Conference Call on November 8, 2023

• BioCardia Announces Completion of Enrollment in Phase III CardiAMP HF Trial and Plans for CardiAMP HF Trial II

• BioCardia Announces Clarification and Next Steps on its Autologous CardiAMP Cell Therapy Programs

• BioCardia Announces Interim Efficacy Results in Phase III Pivotal CardiAMP Cell Therapy Heart Failure Trial

• BioCardia Reports Second Quarter 2023 Business Highlights And Financial Results

• BioCardia to Host Q2 2023 Financial Results and Corporate Update Conference Call on August 9, 2023

• BioCardia Announces DSMB Recommendation to Pause New Enrollment in Phase III Pivotal CardiAMP Cell Therapy Heart Failure Trial While Additional Blinded Data is Collected

• BioCardia Completes Submission of CardiAMP Cell Therapy System in Heart Failure to Japan’s Pharmaceutical Medical Device Agency

• BioCardia Announces FDA Completes Review of Proposed Adaptive Statistical Analysis Design for Ongoing CardiAMP Cell Therapy in Heart Failure Pivotal Study

• BioCardia Announces Helix™ Biotherapeutic Delivery Patent Issuance in Japan

• BioCardia Announces Timing of the Next Data Safety Monitoring Board Meeting for the CardiAMP Cell Therapy in Heart Failure Pivotal Study

• BioCardia Reports First Quarter 2023 Business Highlights and Financial Results

• BioCardia Announces US Patent on Bone Marrow Derived Neurokinin-1 Receptor Positive (NK1R+) Mesenchymal Stem Cells for Therapeutic Applications

• BioCardia to Host Q1 2023 Financial Results and Corporate Update Conference Call on May 10, 2023

• BioCardia Presentations at Next Generation Cardiovascular Drug Development Summit Now Available

• BioCardia Announces Issuance of Two Patents Related to Technology That Guides Interventional Therapies

• BioCardia Reports Fourth Quarter and Full Year 2022 Business Highlights and Financial Results

• BioCardia to Host 2022 Financial Results and Corporate Update Conference Call on March 29, 2023

• Positive Echocardiography Data from BioCardia Phase III CardiAMP Cell Therapy Heart Failure Trial Presented at American College of Cardiology Annual Meeting

• BioCardia and CellProthera Enhance Collaboration for Development of ProtheraCytes™ for the Treatment of Acute Myocardial Infarction in Europe and Potential Early Access for Patients

2022

• BioCardia Letter to Shareholders

• BioCardia Announces $3.6 Million Private Placement of Common Stock

• BioCardia Announces FDA Approval of IND Application for Allogeneic NK1R+ Human Mesenchymal Stem Cells for Ischemic Heart Failure

• BioCardia Reports Third Quarter 2022 Business Highlights and Financial Results

• BioCardia to Host Q3 2022 Financial Results and Corporate Update Conference Call on November 9, 2022

• BioCardia Presents Positive CardiAMP Cell Therapy Heart Failure Trial Two-Year Data at HFSA Annual Meeting

• CardiAMP Cell Therapy Heart Failure Trial Two Year Roll-In Cohort Data to be Presented at Heart Failure Society of America Annual Meeting

• BioCardia Announces Participation at H.C. Wainwright Global Investment Conference September 12-14, 2022 (HYBRID CONFERENCE)

• BioCardia to Participate in Cantor Fitzgerald’s Cell and Genetic Medicines Conference

• BioCardia Announces Positive DSMB Review and Recommendation to Continue Phase III Pivotal CardiAMP Cell Therapy Heart Failure Trial

• BioCardia Enters Agreement with BlueRock Therapeutics to Provide Enabling Catheter Biotherapeutic Delivery Product Candidates for BlueRock’s Cell Therapy to Treat Heart Failure

• BioCardia Reports Second Quarter 2022 Business Highlights and Financial Results

• BioCardia to Host Q2 2022 Financial Results and Corporate Update Conference Call on August 10, 2022

• BioCardia Announces First Canadian Clinical Site for CardiAMP Cell Therapy Heart Failure Trial

• BioCardia to Participate in Upcoming Heart and Pulmonary Therapy Development Symposia

• BioCardia Announces US Patent on Imaging System for Targeting Cardiac Therapies

• BioCardia Reports First Quarter 2022 Business Highlights and Financial Results

• BioCardia to Host Q1 2022 Financial Results and Corporate Update Conference Call on May 11, 2022

• BioCardia Announces FDA Approval of Its IND for NK1R+ Mesenchymal Stem Cells for the Treatment of Patients Recovering from Acute Respiratory Distress due to COVID-19

• BioCardia Reports 2021 Financial Results and Recent Business Highlights

• BioCardia to Host 2021 Financial Results and Corporate Update Conference Call on March 29, 2022

• BioCardia Announces New Center for Medicare and Medicaid Services Reimbursement Code Applicable to the CardiAMP Cell Therapy Procedure

• BioCardia Receives No Objection Letter from Health Canada, Enabling Company to Expand CardiAMP Cell Therapy Heart Failure Trial into Canada

• BioCardia Announces Positive DSMB Review and Recommendation to Continue Phase III Pivotal CardiAMP Cell Therapy Heart Failure Study as Designed

• BioCardia Receives FDA Breakthrough Device Designation for CardiAMP Cell Therapy System for Heart Failure

• BioCardia Announces Participation at the Upcoming Digital Medicine & Medtech Showcase and the H.C. Wainwright BioConnect Virtual Conference