pipeline

Market Opportunity

Ischemic Heart Failure (HF)

• Heart Failure affects 5.7 million people in the U.S. and 26 million worldwide. It is a chronic disease with 50% mortality at five years and impacts 1 in 5 adults over the age of 40.

• The total costs associated with heart failure in the U.S. is estimated to be $39 billion annually and is projected to increase to $70 billion in 2030, with half of the costs related to hospitalization.

Chronic Myocardial Ischemia (CMI)

• Patients with Chronic Myocardial Ischemia suffer from poor perceived health status and psychological distress, have significant impairment in quality of life, and represent a burden to the healthcare system due to significant use of resources.
• It is estimated that between 600,000 and 1.8 million patients suffer from refractory angina, with approximately 75,000 new cases diagnosed each year.